n?=?4 mice for WT, three mice for iDKO and two mice for iKO: WT vs

n?=?4 mice for WT, three mice for iDKO and two mice for iKO: WT vs. archive provides the IHC pictures for just one WT and one iDKO useful for the quantitative evaluation shown in Shape 3G. Leica SP8 confocal lif pictures had been prepared using Imaris software program and preserved as tiffs. elife-50138-fig3-data1.zip (31M) GUID:?12C8C305-7ABC-42C9-92E5-D46C4BFAE43D Shape 3source data 2: Source documents for Ki67+ SC data. The IHC is contained by This zip archive for just one WT and one iDKO useful for quantitative analysis shown in Figure 3H. Outcomes and quantitation demonstrated in the Tazemetostat hydrobromide Shape utilized BD #550609 anti-Ki67. These total outcomes had been verified utilizing a second antibody, Abcam #abdominal15580 anti-Ki67. Pictures using both antibodies are contained in the zip archive, in the indicated folders. Leica SP8 confocal lif pictures had been prepared using Imaris software program and preserved as tiffs. elife-50138-fig3-data2.zip (66M) GUID:?71F1FD5F-F589-4897-8C5F-692B41EB593B Shape 3source data 3: Resource documents for graphs quantifying Yap/Taz+ SCs, EdU+ SCs, Ki67+ SCs, and total SCs. This zip archive provides the organic data for WT and iDKO useful for the quantitative evaluation shown in Shape 3F, G, I and H. The info are within both a text message record and an Excel document, both called Mann Whitney data. These documents consist Tazemetostat hydrobromide of data for Shape 3figure health supplement 1 also, Numbers 4, ?,5,5, ?,6,6, ?,7,7, ?,shape and 8A8A 8figure health supplement 1E. elife-50138-fig3-data3.zip (12K) GUID:?CEBC448F-87E2-4AF1-BB7E-DB94BA937595 Figure 3figure health supplement 1source data 1: Source files for graph quantifying total SCs. This zip archive provides the organic data for WT and iDKO useful for the quantitative evaluation shown in Shape 3figure health supplement 1E. The info are within both a text message record and an Excel document, both called Mann Whitney data. These documents also consist of data for Shape 3figure health supplement 1, Numbers 4, ?,5,5, ?,6,6, ?,7,7, ?,88 and Shape 8figure health supplement 1E. elife-50138-fig3-figsupp1-data1.zip (12K) GUID:?2E8711F7-DE6A-493E-84D0-4AB0D755392C Shape 4source data 1: Source files for c-Jun+ SC data. The IHC is contained by This zip archive for just one WT and one iDKO useful for quantitative analysis shown in Figure 4E. Leica SP8 confocal lif pictures had been prepared using Imaris software program and preserved as tiffs. elife-50138-fig4-data1.zip (55M) GUID:?D81F1161-8598-4B18-9233-8F23EE82046A Shape 4source data 2: Source files for graphs quantifying c-Jun+ SCs, pc-Jun+ SCs, p75+ SCs, and Oct6+ SCs. This zip archive provides the organic data for WT and iDKO useful for the quantitative Rabbit Polyclonal to Cyclin F evaluation shown in Shape 4E, F, H and G. The info are within both a text message record and an Excel document, both called Mann Whitney Tazemetostat hydrobromide data. These documents also consist of data for Shape 3figure health supplement 1, Numbers 5, ?,6,6, ?,7,7, ?,88 and Shape 8figure health supplement 1E. elife-50138-fig4-data2.zip (12K) GUID:?919D6898-77B5-4D42-8670-57E13374B1F4 Shape 4source data 3: European blotting analysis of restoration Schwann Tazemetostat hydrobromide cell markers. Uncropped Traditional western blots of pictures used to create Figure 4figure health supplement 1. Individually prepared examples from 2 WT (#656, #625) and 2 iDKO mice (#378, #379) are demonstrated and useful for quantification. The next figure supplements are for sale to Shape 4. elife-50138-fig4-data3.jpg (668K) GUID:?89023483-3C09-4D43-B44E-D60A4C495E65 Figure 4figure supplement 1source data 1: Source files for graphs quantifying c-Jun, pc-Jun, p75 and Oct6 Westerns. This zip archive provides the organic data for WT and iDKO useful for the quantitative evaluation shown in Shape 4figure health supplement 1. Data are in GraphPad Prism documents, as indicated. elife-50138-fig4-figsupp1-data1.zip (71K) GUID:?53D9CB52-E524-4077-93C8-50C3069272DC Shape 5source data 1: Resource files for TEM data. This zip archive provides the TEM pictures for just one WT and one iDKO useful for quantitative evaluation shown in Shape 5GCI. Images had been taken Tazemetostat hydrobromide utilizing a JEOL 1010 electron microscope installed having a Hamamatsu camera and AMT Benefit image capture software program. Contrast from the pictures was modified using Photoshop software program. The images with this archive were useful for the analysis in Figure 7 also. elife-50138-fig5-data1.zip (71M) GUID:?5FC80172-BD0D-44D2-9CA7-E290046FE128 Figure 5source data 2: Source files for graphs quantifying TEM data. This zip archive provides the organic data for WT and iDKO useful for the quantitative evaluation shown in Shape 5F, G, H and I. The info are within both a text message record and an Excel document, both called Mann Whitney data. These documents also consist of data for Shape 3figure health supplement 1, Numbers 3, ?,4,4, ?,6,6, ?,7,7, ?,8A,8A, Shape 8figure health supplement 1A. elife-50138-fig5-data2.zip (12K) GUID:?72501C22-6093-4CB3-9FA9-4E3EAB6DC959 Figure 6source data 1: Resource files for graphs quantifying axon density and amount of longest axon. This zip archive provides the organic data for WT and iDKO useful for the quantitative evaluation shown in Shape 6E and F. The info are within both a text message record and an Excel document, both called Mann Whitney data. These documents also consist of data for Shape 3figure health supplement 1, Numbers 3, ?,4,4, ?,5,5, ?,7,7, ?,8A,8A, Shape 8figure health supplement 1E. elife-50138-fig6-data1.zip (2.7M) GUID:?2BE6E959-A5CF-4970-B237-0BD586407C4F Shape 7source data.